Symptoms of Hepatitis C
Long term Infection with Hepatitis C (HCV) or chronic Hepatitis C:
Most if not all hepatitis C infection start as an acute phase. This phase of hepatitis C usually goes undiagnosed. However, the signs and symptoms as mentioned above usually occur after being exposed to the hepatitis C virus 1 to 3 months after exposure.
Not all acute hepatitis C infections become chronic. Some fortunate individuals clear hepatitis C in the acute phase. This is called spontaneous viral clearance and it occurs at a rate of 15% to 20% for acute hepatitis C patients.
- dark colored urine
- poor appetite
- fatigue (tiredness)
- slurred speech
- yellow discoloration of the eyes and skin (jaundice)
- spider like blood vessels on skin (spider angiomas)
- weight loss
- bleeding easily
- bruising easily
- muscle aches
- fluid buildup in the abdomen (ascites)
- itchy skin
Ninety five percent of all acute hepatitis c patients based on their genotypes(learn more) can clear the virus with direct acting antivirals or DAAs.
There are many direct acting antivirals and all of them are cost prohibitive. The most popular hepatitis C treatment is called Harvoni. Harvoni is made of ledipasvir 90mg and sofosbuvir 400mg. This hepatitis C treatment cost over $95,000 for 12 weeks treatment, that’s 84 tablets total.
The other direct acting antivirals are equally expensive like Sovaldi, made of sofosbuvir 400mg. The pan genotype (for all genotypes) hepatitis C treatment is called Epclusa. Epclusa is made of velpatasvir 100mg and sofosbuvir 400mg.
The newest direct acting antiviral that has recently been approved by the FDA is Mavyret. Mavyret is made of glecaprevir and pibrentasvir.
Mavyret treats genotypes 1 through 6 who have cirrhosis or don’t have cirrhosis. Also those hepatitis C patients on dialysis. Mavyret is only an eight week treatment compared to Harvoni, Sovaldi and Epclusa.
The cost of Mavyret is approximately $27,000, almost $60,000 less than Harvoni, Sovaldi or Epclusa.
How to order licensed generic hepatitis C treatments? Learn more here.