HCV ab (hepatitis C antibody)

HCV ab or Hepatitis C Antibody

hepatitis c antibodies hcv ab
Hepatitis C antibodies or HCV ab

When hepatitis C virus (HCV) enters the body, your body reacts to the virus infection. Just like a cold or a flu virus.

Our body releases proteins to fight the virus, these proteins are called antibodies.

Once HCV is present in our body, it will always show that you have an antibody for hepatitis C virus, even after you successfully complete your treatment.

What is the HCV ab test?

Hepatitis C antibodies test or HCV ab test
What Is HCV Viral Load?buy generic harvoni online $1495 12 weeks 84 tablets, generic sovaldi online $695 12 weeks 84 tablets, generic epclusa online $2195 12 weeks 84 tablets, generic daklinza online $695 12 weeks 84 tablets

Dr. Pearlman: Viral load is [the number of] viral particles floating in the blood. These are copies of the genetic material of the virus circulating through the body.

Dr. Anania: Viral load is based on technology that lets us measure extremely small quantities of hepatitis C virus RNA, the building block of the virus.

Can I Be Positive for Hepatitis C if I Don’t Have any Measurable Viral Load?

Dr. Pearlman: Being “hepatitis C positive” means you have anti-HCV antibodies in your blood. Having HCV antibodies just means you’ve been exposed to the hepatitis C virus. You can certainly be antibody positive and not have any measurable viral load. One lucky thing this might mean is that you are one of the nearly 20% of people who naturally clear the virus from their bodies. The other possibility is that the virus, during the time blood is drawn, was only temporarily undetectable. HCV viral load in the blood goes up and down, and the test might have caught it on a downswing. So before we tell someone they are negative, we ask them to have the test repeated.

Dr. Anania: After hepatitis C treatment, people still have antibodies to HCV. But if they have no detectable HCV viral load, that indicates recovery from infection — that is, response to treatment and sustained remission. Over a period of time, if a later viral load test comes back undetectable, that patient is in remission.

generic harvoni price in india $1495 12 weeks 84 tablets, generic sovaldi price in india $695 12 weeks 84 tablets, generic epclusa price in india $2195 12 weeks 84 tablets, generic daklinza price in india $695 12 weeks 84 tabletsWhat Is a High Viral Load and Low Viral Load?

Dr. Pearlman: Anything over 800,000 IU/mL is usually considered high. Anything under that is low viral load … Those with low viral load have a better chance of responding to treatment.
Am I Getting Sicker if My Viral Load Is Rising?

Dr. Anania: Not necessarily. With HCV, viral burden in hepatitis C does not necessarily predict the natural history of clinical disease. And therefore, patients need to understand that we use that measurement to help us guide therapy and response to therapy. We use it in conjunction with other types of laboratory data — liver enzymes, liver biopsies sometimes, and viral genotype. Taken all together, these tests give us a snapshot of what is going on. But viral load numbers themselves do not predict disease.

Dr. Pearlman: Unlike HIV, HCV viral copies do not directly affect a patient’s prognosis and how fast disease is progressing in the liver. Remember, we are measuring blood levels, not what is happening in liver cells. HIV viral load does have a lot to do with quicker progression to AIDS. But HCV viral load does not tell you how fast hepatitis is progressing.
Does a Drop in Viral Load Mean Treatment Is Working?

Dr. Pearlman: We often talk about viral load numbers, but we really look at this in terms of logarithms. A “1 log” change is a 10-fold difference. Significant changes in viral load are a 2-log difference or a 100-fold change. This can be deceptive. If you have a viral load of 800,000 and it drops to 400,000, that seems like a big drop. But it’s only changed by a factor of two. A change from 800,000 to 8,000 would be significant. This is important when we look at response to treatment. Twelve weeks after starting treatment, we see if a person’s viral load has dropped 2 logs or more from baseline. If it has not, we are almost sure the treatment is not going to work.
How Long Must a Viral Load Be Undetectable Before Someone Is “Cured?”

Dr. Anania: Generally we like to see six months of continued undetectable viral load after treatment to say a patient’s virus is in remission. I cannot say they are “cured.”

Dr. Pearlman: After treatment, [patients] have a “sustained virologic response” or SVR. That is defined as undetectable viral load by PCR to under 50 IU/mL for 24 weeks after treatment is completed. If that is the case, that is an SVR. SVR means it’s 98% certain you are cured. But there are very rare cases where people relapse if you check their viral load a year or two out. But it doesn’t mean you can’t get hepatitis C again if you engage in high-risk behaviors.
Does Viral Load Respond Differently to Different Hepatitis C Treatments?

Dr. Pearlman: The two major pegylated interferon products for treating hepatitis C — Pegasys and Peg-Intron in combination with ribavirin — in general show similar response rates. Slight variations may be reported in different clinical trials with different subsets of patients.

What Are the Different Ways of Measuring HCV Viral Load?

Dr. Pearlman: RNA is the genetic material all these tests measure. Most experts measure it by a technique called RNA polymerase chain reaction or PCR. There’s also a technique called branched chain DNA, and a newer technique called transcription mediated amplification or TMA. These are just different ways of measuring HCV RNA. TMA probably gets down to detecting the fewest number of copies, but most labs use PCR.

HCV Viral Load Used to Be Measured in Number of Copies. Now They Use International Units. Why?

Dr. Pearlman: Different laboratories don’t use the same standard for counting copies of HCV RNA. So we’re now moving to an international standard.

Dr. Anania: You can still get a copy number. But using international units (IU) is a way to uniformly report data throughout the world. Many lab tests are reported in this way. It standardizes test results between different labs.”

Please give us a call at 1-858-952-1077 or email us viral load results at hcvmeds@gmail.com.  We always, WE MEAN ALWAYS want to know how well the treatment worked to cure hepatitis C infection.  The more information and data we have about your cure rate, the more confidence the world will be about generics of Harvoni, Sovaldi, Epclusa and Daklinza manufactured in India.

Our goal is to make a large impact for the hepatitis C communities around the world.
Hepatitis C antibodies test or HCV ab test

HCV ab test is a simple diagnosis for the hepatitis C virus. If the HCV ab test comes back negative, it means you have not been previously been exposed to the virus.

If the HCV ab test comes back positive, you have been exposed to the virus.

The next step in the procedure is to take the HCV RNA PCR test.

What next if HCV ab is positive?

Once HCV is present in our body, it will always show that you have an antibody for hepatitis C virus, even after you successfully complete your treatment.  
What is the HCV ab test?
Hepatitis C antibodies test or HCV ab test What Is HCV Viral Load?buy generic harvoni online $1495 12 weeks 84 tablets, generic sovaldi online $695 12 weeks 84 tablets, generic epclusa online $2195 12 weeks 84 tablets, generic daklinza online $695 12 weeks 84 tablets Dr. Pearlman: Viral load is [the number of] viral particles floating in the blood. These are copies of the genetic material of the virus circulating through the body. Dr. Anania: Viral load is based on technology that lets us measure extremely small quantities of hepatitis C virus RNA, the building block of the virus. Can I Be Positive for Hepatitis C if I Don’t Have any Measurable Viral Load? Dr. Pearlman: Being “hepatitis C positive” means you have anti-HCV antibodies in your blood. Having HCV antibodies just means you’ve been exposed to the hepatitis C virus. You can certainly be antibody positive and not have any measurable viral load. One lucky thing this might mean is that you are one of the nearly 20% of people who naturally clear the virus from their bodies. The other possibility is that the virus, during the time blood is drawn, was only temporarily undetectable. HCV viral load in the blood goes up and down, and the test might have caught it on a downswing. So before we tell someone they are negative, we ask them to have the test repeated. Dr. Anania: After hepatitis C treatment, people still have antibodies to HCV. But if they have no detectable HCV viral load, that indicates recovery from infection — that is, response to treatment and sustained remission. Over a period of time, if a later viral load test comes back undetectable, that patient is in remission. generic harvoni price in india $1495 12 weeks 84 tablets, generic sovaldi price in india $695 12 weeks 84 tablets, generic epclusa price in india $2195 12 weeks 84 tablets, generic daklinza price in india $695 12 weeks 84 tabletsWhat Is a High Viral Load and Low Viral Load? Dr. Pearlman: Anything over 800,000 IU/mL is usually considered high. Anything under that is low viral load … Those with low viral load have a better chance of responding to treatment. Am I Getting Sicker if My Viral Load Is Rising? Dr. Anania: Not necessarily. With HCV, viral burden in hepatitis C does not necessarily predict the natural history of clinical disease. And therefore, patients need to understand that we use that measurement to help us guide therapy and response to therapy. We use it in conjunction with other types of laboratory data — liver enzymes, liver biopsies sometimes, and viral genotype. Taken all together, these tests give us a snapshot of what is going on. But viral load numbers themselves do not predict disease. Dr. Pearlman: Unlike HIV, HCV viral copies do not directly affect a patient’s prognosis and how fast disease is progressing in the liver. Remember, we are measuring blood levels, not what is happening in liver cells. HIV viral load does have a lot to do with quicker progression to AIDS. But HCV viral load does not tell you how fast hepatitis is progressing. Does a Drop in Viral Load Mean Treatment Is Working? Dr. Pearlman: We often talk about viral load numbers, but we really look at this in terms of logarithms. A “1 log” change is a 10-fold difference. Significant changes in viral load are a 2-log difference or a 100-fold change. This can be deceptive. If you have a viral load of 800,000 and it drops to 400,000, that seems like a big drop. But it’s only changed by a factor of two. A change from 800,000 to 8,000 would be significant. This is important when we look at response to treatment. Twelve weeks after starting treatment, we see if a person’s viral load has dropped 2 logs or more from baseline. If it has not, we are almost sure the treatment is not going to work. How Long Must a Viral Load Be Undetectable Before Someone Is “Cured?” Dr. Anania: Generally we like to see six months of continued undetectable viral load after treatment to say a patient’s virus is in remission. I cannot say they are “cured.” Dr. Pearlman: After treatment, [patients] have a “sustained virologic response” or SVR. That is defined as undetectable viral load by PCR to under 50 IU/mL for 24 weeks after treatment is completed. If that is the case, that is an SVR. SVR means it’s 98% certain you are cured. But there are very rare cases where people relapse if you check their viral load a year or two out. But it doesn’t mean you can’t get hepatitis C again if you engage in high-risk behaviors. Does Viral Load Respond Differently to Different Hepatitis C Treatments? Dr. Pearlman: The two major pegylated interferon products for treating hepatitis C — Pegasys and Peg-Intron in combination with ribavirin — in general show similar response rates. Slight variations may be reported in different clinical trials with different subsets of patients. What Are the Different Ways of Measuring HCV Viral Load? Dr. Pearlman: RNA is the genetic material all these tests measure. Most experts measure it by a technique called RNA polymerase chain reaction or PCR. There’s also a technique called branched chain DNA, and a newer technique called transcription mediated amplification or TMA. These are just different ways of measuring HCV RNA. TMA probably gets down to detecting the fewest number of copies, but most labs use PCR. HCV Viral Load Used to Be Measured in Number of Copies. Now They Use International Units. Why? Dr. Pearlman: Different laboratories don’t use the same standard for counting copies of HCV RNA. So we’re now moving to an international standard. Dr. Anania: You can still get a copy number. But using international units (IU) is a way to uniformly report data throughout the world. Many lab tests are reported in this way. It standardizes test results between different labs.” Please give us a call at 1-858-952-1077 or email us viral load results at hcvmeds@gmail.com. We always, WE MEAN ALWAYS want to know how well the treatment worked to cure hepatitis C infection. The more information and data we have about your cure rate, the more confidence the world will be about generics of Harvoni, Sovaldi, Epclusa and Daklinza manufactured in India. Our goal is to make a large impact for the hepatitis C communities around the world.
Hepatitis C antibodies positive or HCV ab test positive

Your doctor will ask you to take a couple more tests, which is the normal procedure.

The first test is the HCV RNA PCR (genetic material like DNA) test. There are two types of HCV RNA PCR tests, they are:

  1. Qualitative (is the hepatitis C virus present in the blood sample)
  2. Quantitative (if hepatitis C virus is present, how much of it is present)
PCR (polymerase chain reaction) is the process of taking genetic material and duplicating many times over.  This allows to take a small sample of blood and duplicate it millions of times over for multiple testing.

If the qualitative test comes back without HCV present, then previously there was an exposure to the virus but now its not detectable.

If the exposure was recent (a few weeks), it may take up to 6 months for it to be detected. A retest should be done after 6 months.

If the quantitative test (HCV viral load test) shows how much HCV is in the blood sample.


5 Reasons: Hepatitis C Testing and Treatment
 

hepatitis C testing and treatment babyboomers 93% cure rateAs far as viruses go, hepatitis C is among the infectious out there. Once it’s in your blood, it travels to your liver, where it may settle in for a silent, long-term stay. This can lead to cancer or cause the organ to fail if you don’t treat it. In fact, hepatitis C is the top reason for liver transplants in the U.S.  Most folks don’t even know, so they never think about getting Hepatitis C Testing & Treatment.

If you think you’ve been exposed, here are five reasons to get tested right away:

 
1. Hepatitis C Testing and Treatment should be done even if you feel fine.

 
2. The test is quick and easy.

A simple blood test can tell if you’ve ever had the virus. The results usually come back in a few days, but some clinics have rapid versions that can be read in as little as 20 minutes. If it comes back negative, but there’s a chance you were exposed in the last 6 months, get tested again.

If the first results are positive, you had hepatitis C at some point. A second test will check to see if the original case cleared up or became chronic (as it does in most people). If it’s chronic, you’ll need to see a doctor who specializes in treating the disease.
3. You can protect your family and friends.

You can pass the hepatitis C virus to others through your blood, even if you don’t have any symptoms. To prevent this, cover wounds carefully and avoid sharing:

    Razors, nail clippers, toothbrushes, or diabetes supplies
    Needles for injecting drugs, or steroids
    Tools for body piercings or tattoos

Hepatitis C doesn’t spread through kissing, coughing, sneezing, or sharing eating utensils. It’s rare, but you can get it from unprotected sex.
4. Treatments can suppress or even wipe out the virus.

Hepatitis C is treated with a combination of medications called antivirals. For many people, they get rid of the virus completely. They do have serious side effects and they don’t work for everyone. New drugs recently approved by the FDA are more effective and have fewer side effects. But some are expensive.
5. Early treatment can help you prevent liver cancer or liver failure.

According to the CDC, out of every 100 people with hepatitis C:

    60-70 will develop chronic liver disease.
    Up to 20 will get cirrhosis, a dangerous scarring of the liver.
    1-5 will die from liver cancer or liver failure.

Getting tested and treated early can stop the hepatitis C virus from triggering cirrhosis or cancer. Your doctor will be able to keep an eye out for signs of liver trouble. He can start treatment before you serious damage starts.
HCV RNA PCR Test Positive

If its less than 10 IU/L then most probably there is no active hepatitis C infection.

If it is above 800,000 IU/L then it is an active hepatitis C infection.

Take these viral load test results with a grain of salt, until a consulting physician gives their opinion.

Viral loads test numbers should be discussed with a doctor

There is a lot of debate among scientists, researchers and doctors what is the HCV RNA range for an active infection.

Its important to consult with a doctor to really understand the HCV RNA PCR test results.

HCV RNA PCR Test and Genotypes

As mentioned earlier HCV is hepatitis C virus, RNA is the genetic material of the HCV virus and PCR is duplication of the virus many times over for testing purposes.

Every individual with a hepatitis C infection will have a genetic marker called the genotype. The genotype of the virus will never change.

There are 6 genotypes of hepatitis C

The genotype will let the doctor know exactly which treatment is best recommended to eliminate the virus infection.

Before starting treatment, the doctor will recommend that you take a LFT.

LFT (Liver Function Test)

LFT is a simple blood test to determine how your liver enzymes are working and the overall health of your liver.